Schizophonia

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About Schizophonia

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  • Birthday 06/05/2003

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    France, Toulouse
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    Male

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  1. I looked at the study and they don't really know the reason. They assume by default a reduction in exitoxicity but that's really weird because normal glutamate levels aren't supposed to be neurotoxic. NMDA receptor agonists can also be used as antidepressants such as dissociatives, so perhaps in fact NMDA antagonism increases overall glutaminergic neurotransmition (by AMPA and glutamate-1), this is the proposed mechanism for the therapeutic qualities Ketamine. Dissociatives also often have a direct effect on monoamines (by blocking DAR and SERT) and DXM has a particular effect on Sigma-1/2 like DMT which is widely suspected of being neuroprotective. There are also effects on acetylcholine and histamine receptors, depending on the dissociative. Increased glutaminergic and/or dopaminergic neurotransmition increases OXPHOS and strongly upregulates neurogenesis and neuroplasticity. Ketamine is known to potently increase neurotrophins.
  2. In fact the sample of people is particularly large, and there is a strong dose-dependent correlation. This is more interesting than I thought, maybe DXM can be good in the long run. Memantine is already used as a treatment for demencia.
  3. If that happens, I would like to give you Perpignan
  4. I was going to insist on writing something complicated but ultimately it's just about giving a little gratitude, a little energy. I think this is the underlying demand. A smiley is best eheh. Yeah there's nowhere to hide. Confident hug* hum..
  5. 👍
  6. White migrants don't attack locals. Just today : https://www.fdesouche.com/2024/04/19/montauban-82-des-migrants-clandestins-attaquent-un-pere-de-famille-pour-le-voler-a-coups-de-barre-de-fer-et-de-machette-en-plein-jour/ It never stops, there are crimes like that everyday nowadays. Yesterday : https://www.ladepeche.fr/2024/04/18/deux-filles-de-6-et-11-ans-agressees-au-couteau-pres-de-leur-ecole-lindividu-interpelle-11898697.php Whatever...
  7. In an alternative world where I have the money to go to Australia maybe On the other hand, I won't suck you
  8. This concerns massive immigration from the countries of the Maghreb, the Middle East and especially Black Africa. To put it bluntly, no one cares about white expats in France. The French like the English.
  9. Yes I understand travel. But i come to the point where the best things i want doesn't need travel.
  10. True But sometime it feels more like reboot on MSDOS when you're normaly on W11. I suddently want do bizard body positions and GDGHDSSHHDSHDSKDSKJDSHJDSJ%%%%%%93837HDHD;;;;;;;;;;...
  11. Everything is polarized. Behind my apparent cynicism, there is detachment.
  12. That said, travel is clearly overrated these days if you're honest with yourself.
  13. Yes. Germany, UK, Sweden, Catalonia and a large number of cities in France.
  14. Either she's a powerful magnetizer, or she forgot her pill.
  15. My trips are almost always pure nonsense