integral

ME/CFS is a general diagnosis -> MCS is the cause. What causes CFS is hormonal problems, hormones being blocked by air born chemicals (MCS).

- OpenEvidence AI

Blog request, corruption in health care, particularly at the practitioner level. Bonus points for epistemic corruption

- OpenEvidence AI Multiple chemical sensitivity (MCS) is characterized by recurrent, multisystem symptoms triggered by low-level chemical exposures that are generally tolerated by the wider population. The evidence base for MCS includes epidemiological, clinical, neurobiological, and genetic studies, but the pathophysiology remains incompletely understood and diagnostic criteria are not universally standardized. Epidemiological studies show that MCS is more prevalent in women, particularly in middle age, and is associated with comorbidities such as fibromyalgia, asthma, and migraine. Symptom patterns typically include hyperosmia, asthenia, dyspnea, cognitive disturbances, and neurocognitive symptoms, with airway and mucous membrane symptoms often presenting first.[1-4] The Quick Environmental Exposure and Sensitivity Inventory (QEESI) is commonly used for case identification in research and clinical settings.[2][4] Neurobiological evidence suggests involvement of sensitization mechanisms, particularly of transient receptor potential (TRP) channels such as TRPV1 and TRPA1, and altered functioning in brain regions associated with sensory processing and affective regulation. Functional imaging and capsaicin challenge studies support these findings.[5-7] The olfactory-limbic model and neural sensitization/kindling hypotheses are prominent, positing that repeated low-level exposures may amplify central nervous system reactivity.[6-7] Genetic studies have identified associations with variants in genes related to chemical detoxification, oxidative stress, inflammation, and neurotransmitter regulation, including the SLC gene superfamily, though findings are inconsistent and require further validation.[5][8-9] Some studies report altered antioxidant enzyme activities (e.g., catalase, glutathione-transferase) in MCS patients.[9] Consensus statements, such as the Italian Expert Consensus, emphasize the need for standardized diagnostic and management approaches, and highlight the lack of evidence-based guidelines for treatment.[10] There is ongoing debate regarding the organic versus psychogenic origins of MCS, but recent literature increasingly supports a multifactorial, biologically plausible model involving gene-environment interactions, neuroimmune mechanisms, and psychosocial factors.[3][5][9-10] In summary, the evidence for MCS encompasses clinical, epidemiological, neurobiological, and genetic domains, but definitive biomarkers and universally accepted diagnostic criteria remain lacking. The syndrome is best understood as a complex, multifactorial condition with both biological and psychosocial components.[1-10] 1.Multiple Chemical Sensitivity Syndrome: A Principal Component Analysis of Symptoms. Del Casale A, Ferracuti S, Mosca A, et al. International Journal of Environmental Research and Public Health. 2020;17(18):E6551. doi:10.3390/ijerph17186551. 2.Multiple Chemical Sensitivity Syndrome: First Symptoms and Evolution of the Clinical Picture: Case-Control Study/­Epidemiological Case-Control Study. Fares-Medina S, Díaz-Caro I, García-Montes R, Corral-Liria I, García-Gómez-Heras S. International Journal of Environmental Research and Public Health. 2022;19(23):15891. doi:10.3390/ijerph192315891. 3.Multiple Chemical Sensitivity Described in the Danish General Population: Cohort Characteristics and the Importance of Screening for Functional Somatic Syndrome Comorbidity-the DanFunD Study. Dantoft TM, Nordin S, Andersson L, et al. PloS One. 2021;16(2):e0246461. doi:10.1371/journal.pone.0246461. 4.Multiple Chemical Sensitivity in Patients Exposed to Moisture Damage at Work and in General Working-Age Population-the SAMDAW Study. Nynäs P, Vilpas S, Kankare E, et al. International Journal of Environmental Research and Public Health. 2021;18(23):12296. doi:10.3390/ijerph182312296. 5.Multiple Chemical Sensitivity: It's Time to Catch Up to the Science. Molot J, Sears M, Anisman H. Neuroscience and Biobehavioral Reviews. 2023;151:105227. doi:10.1016/j.neubiorev.2023.105227. Leading Journal 6.An Olfactory-Limbic Model of Multiple Chemical Sensitivity Syndrome: Possible Relationships to Kindling and Affective Spectrum Disorders. Bell IR, Miller CS, Schwartz GE. Biological Psychiatry. 1992;32(3):218-42. doi:10.1016/0006-3223(92)90105-9. 7.Individual Differences in Neural Sensitization and the Role of Context in Illness From Low-Level Environmental Chemical Exposures. Bell IR, Schwartz GE, Baldwin CM, et al. Environmental Health Perspectives. 1997;105 Suppl 2:457-66. doi:10.1289/ehp.97105s2457. 8.Multiple Chemical Sensitivity and the SLC Gene Superfamily: A Case-Control Study. Alcorta E, Gomez-Diaz C. International Journal of Molecular Sciences. 2025;26(13):6484. doi:10.3390/ijms26136484. New Research 9.The Search for Reliable Biomarkers of Disease in Multiple Chemical Sensitivity and Other Environmental Intolerances. De Luca C, Raskovic D, Pacifico V, Thai JC, Korkina L. International Journal of Environmental Research and Public Health. 2011;8(7):2770-97. doi:10.3390/ijerph8072770. 10.Italian Expert Consensus on Clinical and Therapeutic Management of Multiple Chemical Sensitivity (MCS). Damiani G, Alessandrini M, Caccamo D, et al. International Journal of Environmental Research and Public Health. 2021;18(21):11294. doi:10.3390/ijerph182111294.

@Leo Gura This has to be what you have. I remember you saying you largely gave up on trying to fix your health issues, but also during one of our conversation you said you didnt really try removing all scent/toxins/triggers from the air your breathing. Its likely your in the category of extreme sensitivity MCS. During my early years with this were i had not made the connection yet with MSC i had extreme digestion issues to the point of shitting blood everyday for years + a pletera of other issues. After moving to a new house 90% of my symptoms disappeared. I went 10+ years with devastating health issues before making the connection. Depending on someones genetics there going to react differently to air. The ideal scenario: is living near the water (house on water front) this has the highest air quality because its not concentrated city air (laundry detergents fumes+ ...) Indoor has to have painted walls with Non-VOC paints. HVAC + non-toxic aluminum piping pulling in outdoor air. Vinegar + baking soda is the only cleaning product in your home. Removal of any kind of perfumes/party stuff products you used to wear or any clothes that are contaminated. Hydroxyl machine for decontaminating valuables or handling other scented issues to destroy the scent producing compound at the molecular level. Air purifies are limited because they work best on the particle level and this is a molecular level problem. The next major discovery for a nobel prize winner is to connect the majority of disease to air. I know you have super human intuition but mine is telling me this does not convince you and i have no way to write this out in a way to would bridge the gap. I think it would make sense to at least experiment with this, because its counter-intuitive but still grounded. This is not a rare disease, it effects millions, its just outside the scope of profits. https://aseq-ehaq.ca/en/ Some more info. Low level chemical exposure is devastating and its invisible beyond most intuition, it takes a experience event to make the connection. All it takes is a candle offgassing (not lit) to shut down digestion or + any long list of symptoms depending on how someones genetics will handle the stress.

Everyone, you all have MCS, (multiple chemical sensitivity) You have to look into this very deeply. 99% of issues is MCS.

Why did this pass? Dont they need majority vote?

@Dodo my guy how is a profitable trader, his strategy is to fit a basic trading strategy through back testing every week. And then he just trades that strategy for that week. but most of the profits he made were from picking ICO’s in advance. Right now, he told me about Trump’s finance crypto project I’m not sure what it was called, but it’s not the Trump coin

I don’t try to predict the future I entered the market when there’s very strong obvious opportunities like that were 85% below the all-time high, and it flat lines for like three months right now, it is a bad opportunity to enter the market because bitcoin is at an all-time high So it doesn’t matter if it’s gonna go 3X more it makes no difference. It’s just a bad trade. based on just pure probability but this depends the timeframe we’re talking about, right now I’m talking about the 2 to 4 year

You can't make a girl who's still at stage 2 in sexual development to want anything else but to be fucked. They think making love is fucking, and the only reason you were able to fuck her like that is because you love her. They don't know anything else and of course the connection you actually have with her is shallow, and based on lust + unhealthy dependency that wears off.

i interpreted what you said as, "we are at the bottom" lol I was explaining when the next bottom will be and around what price it would be at. Saying that Bitcoin bottomed a long time ago doesn't help anyone invest, in blindsights them from what the crash is gonna be. There is more downside now than there is upside for anyone freshly investing in the market because Bitcoin is at an all time high. The future is a catastrophic 90% dump like usual, people need to be aware that this is happening. Whatever the all time high is going to be for Bitcoin this cycle subtract 75 to 90% and that's gonna be the bottom for that cycle

1.e4

It’s an outlet that takes humanity’s corruption and channels it somewhere. It likely helps tame men and reduce the level of rape and violence. Same thing with violent video games, helping give men an outlet. But things like Instagram have done the opposite, by feeding and enhancing women’s body image insecurities and relationship standards to a hypergamy mess.

You have to babysit the entire population, that is the mindset when you’re playing with a child, are you gonna get offended and angry? No, of course not you’re far above them Every game they play you play the game with them, you make a game out of every situation

You’re supposed to laugh with them and join them in the fun. When they say stuff like that, laugh and smile, and then they will like you. The problem is you hate them when in reality you should hate everyone equally because they’re all dumbasses So seeing as everyone’s a dumbass, make friends with everyone You’re still very selective about who you like and don’t like and all these games You should have zero expectations and underwhelming degrees of expectations with every person you come in contact with. Your expectations of people are way too high to begin with. You’re trying to make people live up to some standard because you’re not aligned with truth Every person you come to contact with is a desperate survival self deceived animal, who is at the whim of every emotional fluctuation, which they have no control over. It’s like expecting a dog to behave not like a dog and the only reason you consistently expect more from a dog is because you’re not aligned to the truth and are still living a fantasy