Trying Out a 4-Substituted Tryptamine & More

[Nemra]

@Leo Gura, I don't know why I haven't watched your trip reports.

The way you describe your trip is very helpful in understanding mine.

18 hours ago, Nemra said:

@Leo Gura, which psychedelics do you consider S-tier besides salvia?

Or what makes a psychedelic an S-tier?

Edited 16 hours ago by Nemra

[Leo Gura]

21 hours ago, Nemra said:

@Leo Gura, which psychedelics do you consider S-tier besides salvia?

 

• DMT
• 5-MeO-DMT
• 5-MeO-MALT
• THC
• Salvinorin A

But this will vary by genetics. That's what is S-tier for my system.

Edited 14 hours ago by Leo Gura

[Yali]

@Leo Gura I thought you were serious in your recommendation for most people to NEVER try Salvia?

[Loveeee]

On 11/16/2025 at 7:53 AM, Leo Gura said:

Yes, a lot.

For what purpose ? What's it like ?

[Leo Gura]

17 minutes ago, Yali said:

@Leo Gura I thought you were serious in your recommendation for most people to NEVER try Salvia?

It is only for the most serious and mature minds.

I would not recommend it casually.

It very much depends on dose. It is very easy to over-dose salvia which is what makes it dangerous. You have to be intelligent enough not to over-dose it, but people cannot be trusted to be that intelligent.

Also, my understanding and appreciation of salvia has evolved and matured. It affects me differently now than years ago because I have grown so much.

Edited 13 hours ago by Leo Gura

[Leo Gura]

7 minutes ago, Loveeee said:

For what purpose ? What's it like ?

For the purpose of understanding Reality.

It is infinite consciousness.

[Nemra]

@Leo Gura, what is the difference between S-tier and the other tiers?

[Loveeee]

5 hours ago, Leo Gura said:

For the purpose of understanding Reality.

It is infinite consciousness.

Why not stick to 5meo for that, what's the value of salvia, how does it differ ? 

[Leo Gura]

37 minutes ago, Loveeee said:

Why not stick to 5meo for that, what's the value of salvia, how does it differ ? 

It is significantly different. Gives new angles on Consciousness.

I wasn't able to take 5-MeO for health reasons. 5-MeO is more taxing on the brain.

Salvia has a high weirdness factor, moreso than most chemicals.

Edited 7 hours ago by Leo Gura

[Davino]

Salvia in low doses makes me very wise, calm and present.

Salvia changes a lot depending on the dose.

[Nemra]

11 hours ago, Nemra said:

what is the difference between S-tier and the other tiers?

@Leo Gura, do you rate based on how open-minded it makes you and the depth of experience, comprehension, and clarity?