The 5-MeO-DMT Mega-Thread

[Brivido]

On 05/12/2022 at 5:29 PM, Giulio Bevilacqua said:

Do you take some days off from work before/after  taking 5meo?

The first time you try it, make sure to have at least one day off from work.

The best scenario would be to do it on Friday night and then have the whole weekend to contemplate and integrate your trip.

On Monday you're going to be fine to go back to work, if you start with the right dose.

[Girzo]

Do you remember times that many people on these forums were reporting that they have to dose like 40 mg or more of 5-MeO-DMT to feel a strong trip?

Many people thought back then "must be my high natural tolerance". No, it wasn't. The 5-MeO-DMT Oxalate back then, the brownish product in salt form for plugging or snorting, had been contaminated with synthesis by products UP TO 50%. It was only 50% 5-MeO-DMT in some cases.

So maybe the consideration now should be, that 5-MeO-DMT that is too yellow or too brown is not good.

Here's the photo of failed, weak 5-MeO-DMT Oxalate

Someone tested a sample that was 100% the byproduct, I hope it's only someone's result of attempting to home synth the chem and not something bought and sold on the streets. Here's the photo of 100% synthesis byproduct:

Source: DrugsData.org

[Leo Gura]

I used Oxalate and it is potent as hell, no less than HCl or freebase.

Of course there could have been bad vendors or batches, but tan colored Oxalate is good stuff if from a legit vendor. That first photo looks totally legit. The color is normal and fine. You can't judge potency by color.

If something is only 50% of the promised product that means some middleman cut it. Lab grade stuff is like 98% purity and a lab has no good reason to do 50% synths unless they are total baboons who don't know what they are doing.

I doubt anyone is doing home synth of 5-MeO-DMT. Good labs make it and then some middleman might cut it.

I have never had a bad batch of any chemical. They were all super potent. I have tried over 30 chems from various sources.

Edited January 22, 2023 by Leo Gura

[Grateful Dead]

2 hours ago, Girzo said:

Here's the photo of failed, weak 5-MeO-DMT Oxalate

Mine looks exactly like this and 7 mg is enough for a breakthrough.

[Girzo]

1 hour ago, Leo Gura said:

I doubt anyone is doing home synth of 5-MeO-DMT. Good labs make it and then some middleman might cut it.

Actually, people do, 5-MeO-tryptamine (mexamine) is widely available and legal in many countries. And Hamilton Morris sold like 10.000 copies of pamphlet with synthesis guidelines for amateur cooks (from mexamine exactly). 

There are also internet forums for newbies in synthesis, I am not talking about the old school ones that have something to do with bees and wasps, I am saying about new ones that take inspiration from TV series and they trade precursors openly.

The N-methyl-Pinoline can't be from cut, because it's a by-product (and doesn't appear anywhere ele on the market) of the reaction if there's too much heat, you can see Hamilton Morris synthing 5-MeO in a mexican lab on YT and using dry ice to keep everything cool. Maybe some amateur lab rats heat it too much, rush things or don't have gear to mix everything drop by drop.

Here's a graph comparing pinolene with 5-MeO, it's the same substance, just forming an additional ring. The carbon atom from n-methyl group connects to carbon atom on 2nd postion on the indole part, forming a tryptoline.

It's a year old info, but I have just found it out.

2 hours ago, Leo Gura said:

That first photo looks totally legit. The color is normal and fine. You can't judge potency by color.

Then we are... in a not so good situation. I am curious if someone who still has cache of that 5-MeO from back then would be willing to test it if it's really clean.

[Girzo]

Ah, and this N-methyl-Pinoline fromation can't happen from improper storage conditions, so it has to come from synthesis.

There is a phot of another 5-MeO-DMT that has been verified to be around 10% n-methyl-pinoline. The person sending reported something off about the smell to be the reason for sending this sample.

 

If I were to speculate. Maybe the lab synthing the Oxalate didn't have everything right and made mistakes. There was a period when 5-MeO-DMT had been scarecly available, then the Oxalate came in. Maybe it had been a first try synthing using a new method for this lab and they made a mistake, some parts of the vessel heated too much and substance degraded, while they only tested for purity the parts that didn't undergo the reaction that formed n-methyl-pinoline, unaware that something like this could happen. It's pure speculation, but labs are people too, and they learn new stuff all the time.

AAAND... the Canadians sell Oxalate no more, just freebase. So maybe there really was somthing offf about this method of producing 5-MeO that resulted in Oxalate salt.

Edited January 22, 2023 by Girzo

[Leo Gura]

31 minutes ago, Girzo said:

I am curious if someone who still has cache of that 5-MeO from back then would be willing to test it if it's really clean.

Dude, I did a bunch of that first Oxalate batch. That was right around the time I introduced ya'll to 5-MeO-DMT. It is excellent, pure stuff. I triped balls on it with no problems.

Yellow and brown 5-MeO-DMT is as good as white. Don't be racist.

Edited January 22, 2023 by Leo Gura

[Girzo]

The fact is people have had problems with it and I present a possible explanation why.

[Leo Gura]

4 minutes ago, Girzo said:

The fact is people have had problems with it and I present a possible explanation why.

Maybe it's not the chem but the people.

Must I say it?

"Psychedelics don't work on stupid people." -- Terence McKenna

Edited January 22, 2023 by Leo Gura

[Girzo]

1 minute ago, Leo Gura said:

Maybe it's not the chem but the people.

That's what I have believed. Now, I am having suspisicions.

People are people, labs might cut corners and make mistakes. It's a not so regulated market after all.

Assuming it's lab, because as I have said, there are clandestine homebrew vendors appearing on the Dark Web nowadays.

[Craigxt22]

@Leo Gura  Do you not test your chemicals? I am assuming you don't make them you're self. To me it seems crazy to get hold of them and just consume them because they 'look alright' or is from a trusted vendor.

 

Whenever I get hold of psychedelics I have to test them, even if it's from a trusted source. Even if clear, I still get paranoid, and almost always my paranoia makes my trips hell as I am scared there's a chance I have poisoned myself.

[Girzo]

@Craigxt22 It depends on what you mean by testing, baically no-one tests by sending sample to DrugsData or similar, it costs $100.

But if you want to know approximately the % of purity then it's needed.

[Leo Gura]

8 minutes ago, Craigxt22 said:

Do you not test your chemicals?

Dude, this ain't the FDA.

Edited January 22, 2023 by Leo Gura

[Juan]

22 minutes ago, Leo Gura said:

Dude, this ain't the FDA.

Huh what? @Leo Gura I would agree on this one with @Craigxt22 . I think it would be easy to put something else on some substance. With LSD and MDMA I had done this and you can feel safer and eliminate the thought of “what if I actually ingested another thing aside the real thing?”. I think this is a basic but important suggestion for psychonauts. 

[Juan]

Unless ofc you REALLY REALLY trust your source, maybe is ok, still I like to double check for security. And since also you been working with new and unknown substances, I can understand.

[Girzo]

So, I have listened to Hamilton Morris more, and he is aware of the possibility of the aforementioned impurity forming. And it has been studied by Dennis McKenna, from his research it turns out N-methyl-Pinoline is a very weak iMAO, so it's a lucky situation it's not dangerous.

So it makes the substance impure, but for all practical reasons you can treat it as pure, after adjusting dosages. I would just recommend to be cautious about jumping to high doses when using a new batch, because 40 mg from an old batch might be equal in strength to 30 mg from the new batch.

[t1mb0b]

I searched this forum, and didn't quite find the answer I am looking for. 

Can anyone fill me in on ingesting 5MeO sublingually? I have vaped it (Freebase or Oxalate), insufflated it (HCl and Oxalate), and I've read guides on boofing HCl. I cannot find a guide or how-to on specifically how to dose sublingually. I did try a couple times, up to 30mg, and I am not getting any effect. So, either I am not doing it correctly, or perhaps HCl is not the proper form. I have also read an anecdotal report of someone using freebase and lemon juice. I will try that next.   

Can you ingest HCl sublingually, or does it need to be Fumarate? Is the procedure to place the dose under your tongue for ~15 minutes? Do you swallow it after, or spit it out?

Appreciate any input- if there is a guide, please point me in the direction! All if could find with a Google was a white paper which explains the effects or various RoAs, however no specifics on how to sublingually dose, and a few anecdotal reports.

[Grateful Dead]

I've personally never tried it, but Leo said he's tried and it doesn't work.

[LostSoul]

@t1mb0b i Will be gettin HCI soon, but 5-meo-malt. Do you have any sugestions on how to consume It?

[Andromeda]

Just now watching Leo's "What does awakening feel like?" video after first 5-meo-dmt experience: 

 

Only now do I appreciate how funny this video is. Tears are filling my eyes. 

The "of course..." and "how could I be so stupid" are rather funny and true. How am I ever going to explain this to my loved ones; they will think I went crazy .