5-MeO-DMT for longevity - Bryan Johnson

[Carl-Richard]

32 minutes ago, Leo Gura said:

@Carl-Richard Dr Mike has joined the chat.

Mr.* Mike. I always correct it in my head when I read "Dr. Mike" now. The internet decided to revoke his PhD status.

[cistanche_enjoyer]

4 hours ago, Leo Gura said:

The psychedelc chemical itself is not increasing your health there.

Bro he literally posted about this with proof attached:

+ Accelerated neurogenesis: a single dose more than doubled brain cell proliferation and neuronal regeneration in the hippocampus within 12 hours, alongside measurable increases in synaptic density and firing frequency in rodent models. 

+ Proteomic reorganization: in human cerebral organoids, 5-MeO-DMT triggers rapid proteomic shifts favoring cellular reorganization and synapse formation. Early evidence of structural brain renewal at the molecular level.

+ Default Mode Network reset: The DMN calcifies with age locking us into rigid, repetitive patterns of thought. 5-MeO-DMT disrupts these patterns, restoring bottom up connectivity between sensory and creative brain regions. A forced return to neurological flexibility and youthfulness.

+ Systemic anti-inflammation: suppresses pro-inflammatory cytokines (IL-1β, IL-6, TNF-alpha) while upregulating IL-10, the anti-inflammatory signal. Mediated through the Sigma-1 receptor, suggesting a mechanism distinct from other psychedelics.

[Willy Phallicus]

4 hours ago, Cireeric said:

I definitely wouldnt bet on 5-MeO for longevity, but psylocibin seems very plausible to me.

Shrooms try to kill me every trip now.  Unless we're talking about micro dosing here which I dont bother with.

If psychedelics were that good for you more would be better and that's been proven demonstrably false many times.

The benefits of these types of drugs are mental, not physical - and still subject to abuse like anything else.