5-MeO-DMT for longevity - Bryan Johnson

[Carl-Richard]

1 hour ago, Leo Gura said:

If you think chronic use of 5-MeO-DMT is going to increase your longevity, you're kidding yourself.

*Guy says he is going to do an experiment, perhaps 2-3 trips like with mushrooms, to see what happens to his biomarkers* -> "chronic".

"Epistemic responsibility".

[Cireeric]

1 hour ago, Leo Gura said:

If you think chronic use of 5-MeO-DMT is going to increase your longevity, you're kidding yourself.

I definitely wouldnt bet on 5-MeO for longevity, but psylocibin seems very plausible to me.

[Leo Gura]

7 minutes ago, Carl-Richard said:

*Guy says he is going to do an experiment, perhaps 2-3 trips like with mushrooms, to see what happens to his biomarkers* -> "chronic".

"Epistemic responsibility".

It's even more silly to think that 3 uses of mushrooms will make any improvement to your health.

The only way 5-MeO might increase longevity is if you consume it regularly for years and decades.

No three uses of anything will increase your longevity. This is classic snake oil sales.

If he isn't even prepared to take it chronically for a least a year, he's even less serious than I gave him credit for.

I have taken 5-MeO for over 90 days. I did more experiment on this issue than he is planning to do.

Edited 4 hours ago by Leo Gura

[cetus]

5 minutes ago, Leo Gura said:

The only way 5-MeO might increase longevity is if you consume it regularly for years and decades.

Interesting. What makes you say that? What about long term lsd use?

*Would make for a good YT video.

Edited 4 hours ago by cetus

[Leo Gura]

2 minutes ago, cetus said:

What makes you say that?

I am not saying that. I am saying a thing must be chronic to have a chance of impacting longevity.

There's no pill for longevity. This is a childish idea.

[Leo Gura]

I don't think any psychedelic is healthy for you long-term. Psychedelics have a cost.

Edited 4 hours ago by Leo Gura

[cetus]

10 minutes ago, Leo Gura said:

I am not saying that. I am saying a thing must be chronic to have a chance of impacting longevity.

There's no pill for longevity. This is a childish idea.

If using 5-Meo convinces a smoker to quit that would certainly be a blatant example to live a healthier and longer life. Just as an example.

Edited 4 hours ago by cetus

[Leo Gura]

Just now, cetus said:

If using 5-Meo convinces a smoker to quit that would certainly be a blatant example to live a healthier life. Just as an extreme example.

Sure, that can happen. But that is another matter. The psychedelc chemical itself is not increasing your health there.

If I slap a drug addict across the face, that might help him quit drugs and extend his life. But slapping people isn't good for health.

[Leo Gura]

We have long term studies on weed use, and most signs seem to be negative on brain health.

[cetus]

2 minutes ago, Leo Gura said:

We have long term studies on weed use, and most signs seem to be negative on brain health.

I'm suing my local dispensary. Yesterday when I woke up first thing I did was take a piss. Then got out of bed.

[Leo Gura]

21 minutes ago, cetus said:

I'm suing my local dispensary. Yesterday when I woke up first thing I did was take a piss. Then got out of bed.

I took a shit and stayed in bed.

[Carl-Richard]

2 hours ago, Leo Gura said:

Sure, that can happen. But that is another matter. The psychedelc chemical itself is not increasing your health there.

If I slap a drug addict across the face, that might help him quit drugs and extend his life. But slapping people isn't good for health.

The point isn't whether the chemical has a "purely physical" effect like you're implying (which is an outdated idea by the way). It's whether it can reliably lead to improvements in longevity. If you for example have a spiritual awakening, single events like that have been shown to lead to lasting changes in the brain and thus behavior and thus stress levels and thus health and thus longevity. To think that something must be in some weird way "purely physical" to matter (which nothing truly is when it comes to humans), is an outdated paradigm even in mainstream science.

Edited 2 hours ago by Carl-Richard

[Leo Gura]

35 minutes ago, Carl-Richard said:

It's whether it can reliably lead to improvements in longevity.

This just opens the door a mile wide for these health influencer grifters to sell you snake oil.

Longevity means the chemical increases the health of your body, directly. Not vague lifestyle changes.

Eating your own shit before each meal will increase your longevity just by making you not want to eat.

Anyone want to sign up for Leo's Shit-Eating Course? I promise you longer life. 100% backed by Science™.

I can reduce heart-disease and diabetes across the globe by 50% if everyone just eats a bit of shit before each meal.

Edited 2 hours ago by Leo Gura

[Carl-Richard]

11 minutes ago, Leo Gura said:

This just opens the door a mile wide for these health influencer grifters to sell you snake oil.

Longevity means the chemical increases the health of your body, directly. Not vague lifestyle changes.

Eating your own shit before each meal will increase your longevity just by making you not want to eat.

Anyone want to sign up for Leo's Shit-Eating Course? I promise you longer life. 100% backed by Science™.

I can reduce heart-disease and diabetes across the globe by 50% if everyone just eats a bit of shit before each meal.

In the shit case, you can simply cut the shit and simply not eat. In the spiritual awakening case, it might not be so simple. Psychedelics can help in that regard. Yes, after 100 trips, the differences might not seem to matter anymore, but there are some really depressed, really dysfunctional people other there that might only need a little push before a huge set of bricks (not shit) fall into place.

And people do eat shit to get a better microbiome, but that's a different story.

[Leo Gura]

6 minutes ago, Carl-Richard said:

but there are some really depressed, really dysfunctional people other there that might only need a little push

This doesn't fall under longevity. This is a standard effect of psychedelics which everyone already knows and takes them for.

This is like saying that going to a therapist increases longevity. Yes. Of course. That's why therapists exist. Therapists save lives.

Edited 1 hour ago by Leo Gura

[Carl-Richard]

59 minutes ago, Leo Gura said:

This doesn't fall under longevity.

In your outdated mind-body dualism paradigm, maybe. But in mainstream science, health is bio-psycho-social.

 

59 minutes ago, Leo Gura said:

This is a standard effect of psychedelics which everyone already knows and takes them for.

Then great that a lot of research is being done on it (particularly showing that the mystical experience / spiritual awakening catalyzed by the psychedelic is the predictor for behavioral change, not the mere consumption of it or the "pure physical effect").

 

59 minutes ago, Leo Gura said:

This is like saying going to a therapist increases longevity. Yes. Of course.

Definitely. It has come to this point. I've taken full courses that sole point seemingly was to show how mind and body/physiology are connected.

Edited 59 minutes ago by Carl-Richard

[Leo Gura]

Calling that longevity science is silly to me. Shows how vacuous longevity science is.

Edited 1 hour ago by Leo Gura

[Carl-Richard]

51 minutes ago, Leo Gura said:

Calling that longevity science is silly to me. Shows how vacuous longevity science is.

Not as vacuous as exercise science 💀 And that one is ironically lagging on the bio-psycho-social front (in my narrowly focused opinion).

Edited 56 minutes ago by Carl-Richard

[Leo Gura]

@Carl-Richard Dr Mike has joined the chat.

[Oppositionless]

7 hours ago, OBEler said:

After your kundalini awakening what state are you now in? Do you regret your kundalini awakening?

Not at all, I have a new sense of life purpose.  I miss the crazy spiritual high of the first month though not gonna lie.