Too much or too many supplements might be holding you back

[Carl-Richard]

I've recently tried many supplements, which is popular these days (Bryan Johnson, Dr. Rhonda Patrick, Andrew Huberman, etc.). Before, I had an aversion to B-vitamin supplements because they made me feel too wired, but I decided to still try them in the form of a multivitamin. I also added copious amounts of zinc, boron and vitamin D (and K2, magnesium, calcium, fish oil).

Then after finishing my degree, I noticed I was a bit restless even though I had little reason to be. So I decided to drop the multivitamin to see if indeed it was the B-vitamins. The restlessness dropped noticeably and quite immediately. Then when I try meditating I still find there is some lingering restlessness there. Maybe it's the zinc supplement (which I over time decided to double the dose of, because it gave me more energy).

Also, when I started the boron supplement, I went straight to two pills (6 mg) without starting with one and then deciding whether I should taper up (or drop it). I suspect it could be making me feel a certain way (I have for example had strong reactions to too much Vitamin E, probably due to its anti-oxidant/anti-inflammatory activity, and boron has anti-inflammatory activity).

If I still feel too wired or weird, I will maybe start tapering down vitamin D (which is a bit of a tough nut because I've done it before; but then I also took smaller doses; and I did not respond positively).

[PsychedelicEagle]

I would suggesting measuring before starting any supplementation, if possible.

Then you can assess your baseline and whether supplementing is even necessary.

After you start supplementing, you keep tracking to see if the dose is adequate.

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If you feel 'too-wired' with B vitamins, you could be sensitive to methyl donors. There are supplements that target this type of individual variability, such as: https://www.sunday.de/en/bioactive-b-complex-sensitive.html

Edited yesterday at 04:11 PM by PsychedelicEagle

[Leo Gura]

All those people make millions selling you supplements. Keep that in mind.

[Carl-Richard]

8 hours ago, Leo Gura said:

All those people make millions selling you supplements. Keep that in mind.

Whatchu poppin?

[SimpleGuy]

Having results from supplements requires a lot of money. Not because good supplements are expensive, but because you need to get blood work done using every supplement to check if it is working or not.

[Leo Gura]

5 hours ago, Carl-Richard said:

Whatchu poppin?

These days only Vit D and A.

A is good for eyes. D is good cause I don't get a lot of outdoor sun.

Edited 4 hours ago by Leo Gura

[integral]

On 12/30/2025 at 3:01 PM, Carl-Richard said:

for example had strong reactions to too much Vitamin E, probably due to its anti-oxidant/anti-inflammatory activity,

Maybe because vitamin E supplements are toxic.