Bryan Johnson has Autoimmune, Low Iron and Thyroid desease

[integral]

9 hours ago, Natasha Tori Maru said:

@PsychedelicEagle I think 92ng/ml

When I was vegetarian it was 8 🥹 

It seems I am not able to absorb some types of iron, as I was as getting a lot in my diet (non heme). I added wild kangaroo into my diet 3x a week and my levels shot up quickly. I notice a huge difference between kangaroo meat and beef/veel/lamb digestion, energy and overall health wise. I think the wild culling for consumption (not farmed) makes a difference in can perceive, health wise. 

Got to drink the blood of the animal, my local farm sells grass fed pigs blood. Theres so much heme iron in it you can easily overdose and it doesnt cause digestion stress like supplements.

Edited 23 hours ago by integral

[Leo Gura]

This is the same health condition I've struggled with.

Carnivore diet was the most effective. Eating standard health foods with a leaky gut causes more harm than good.

Low dose naltrexone (LDN) is also effective at curtailing immune system overreaction.

Has he tried LDN? That's a low hanging fruit.

If Bryan has an autoimmune disorder, there is no way he is even in the top 20% of healthy people on this planet. None of his gimmickry can overpower a proper autoimmune disorder. You can't supplement or diet your way out of it.

Edited 18 hours ago by Leo Gura

[cistanche_enjoyer]

1 hour ago, Leo Gura said:

This is the same health condition I've struggled with.

Carnivore diet was the most effective.

What’s your diet like now?

[Leo Gura]

7 hours ago, cistanche_enjoyer said:

What’s your diet like now?

It is not strictly carnivore because it is just impossible to sustain carnivore-only for 5 years straight.

But my ideal diet is carnivore. The closer to carnivore I eat, the better I feel.

Carnivore is also pricey on the budget. I don't want to spend too much money on food.

Edited 12 hours ago by Leo Gura

[PsychedelicEagle]

20 hours ago, Natasha Tori Maru said:

liquid or pills? I was using floridix floravital for 6 months which took my ferratin from 8 -> 24 but couldn't move the needle past that point without red meat.  Pills make me severely constipated.

Pills. For me they seem to work OK. Every other day, I'm taking a 22.5mg elemental iron supplement with iron glycinate and lactate — it seems smoother on the digestive tract. But thanks for the tip — I hadn't considered liquid form — it could also be easier in not needing to time it with meals.

Edited 12 hours ago by PsychedelicEagle

[PsychedelicEagle]

9 hours ago, Leo Gura said:

Low dose naltrexone (LDN) is also effective at curtailing immune system overreaction.

Has he tried LDN? That's a low hanging fruit.

Interesting alternative indeed — I've heard of this protocol in the past.

Have you had success using it yourself, @Leo Gura?

[Leo Gura]

15 minutes ago, PsychedelicEagle said:

Interesting alternative indeed — I've heard of this protocol in the past.

Have you had success using it yourself, @Leo Gura?

Yes. It is one of the only things that I tried that worked.

It is not 100% effective. Maybe 50% effective for me. But that 50% is a life-changer.

I think the problem is that the body develops tolerance to any chronic medicine after months of daily use. LDN seems to become less effective over time.

Edited 11 hours ago by Leo Gura

[PsychedelicEagle]

1 hour ago, Leo Gura said:

Yes. It is one of the only things that I tried that worked.

It is not 100% effective. Maybe 50% effective for me. But that 50% is a life-changer.

Good to hear.

1 hour ago, Leo Gura said:

I think the problem is that the body develops tolerance to any chronic medicine after months of daily use. LDN seems to become less effective over time.

Makes sense. Could it also be a drift off your individual's optimal dose, i.e., have you tried lowering or raising the dose, or cycling the medication? Anyway, I'm not a doctor, just reasoning around it from the little mechanistic understanding I have: briefly blocking receptors to create a compensatory upregulation. So each person should have their individual sweet spot between blocking too much or blocking too little, that can fluctuate over time.

[integral]

5 hours ago, PsychedelicEagle said:

22.5mg elemental iron supplement

22.5mg of iron = 3 tablespoons of pigs blood.

Edited 6 hours ago by integral

[PsychedelicEagle]

@integral High heme iron intake correlates with elevated iron stores but also with cardiometabolic risk. There are many mechanisms that try to explain this correlation. Not saying you should never consume heme iron, but doing it too often is likely to be detrimental rather than beneficial, AFAIA, especially if one is not donating blood.

The major benefit of supplementing with non-heme iron is that the bodily mechanisms controlling iron uptake are not hijacked by the porphyrin ring surrounding heme iron. Personally, I think it's healthier to have ferritin in the 30s ng/ml rather than in the >100s ng/ml, but I'm aiming for the 70ng/ml sweet spot.

Edited 6 hours ago by PsychedelicEagle

[OBEler]

15 hours ago, Leo Gura said:

This is the same health condition I've struggled with.

Carnivore diet was the most effective. Eating standard health foods with a leaky gut causes more harm than good.

Low dose naltrexone (LDN) is also effective at curtailing immune system overreaction.

Has he tried LDN? That's a low hanging fruit.

If Bryan has an autoimmune disorder, there is no way he is even in the top 20% of healthy people on this planet. None of his gimmickry can overpower a proper autoimmune disorder. You can't supplement or diet your way out of it.

I have the feeling, Bryan watched your content. He teaches self help and also takes 5 meo dmt.  For sure he didnt came to the idea by himself to take some 5 meo. That was probably you. Also it makes sense if you enter the business of self help to check content of other self help teachers out.

He looks sick. He will put all his energy to fight this disease. Maybe you can contact him and help him out what worked for you? 

Edited 6 hours ago by OBEler

[integral]

3 hours ago, PsychedelicEagle said:

@integral High heme iron intake correlates with elevated iron stores but also with cardiometabolic risk. There are many mechanisms that try to explain this correlation. Not saying you should never consume heme iron, but doing it too often is likely to be detrimental rather than beneficial, AFAIA, especially if one is not donating blood.

The major benefit of supplementing with non-heme iron is that the bodily mechanisms controlling iron uptake are not hijacked by the porphyrin ring surrounding heme iron. Personally, I think it's healthier to have ferritin in the 30s ng/ml rather than in the >100s ng/ml, but I'm aiming for the 70ng/ml sweet spot.

Had a long debate on this topic

Science is useful as a general intuition after you put hard work verifying whether something is true for yourself through your own observation and experiments, but when someone points to these logical sequences of how the body works like you have and then tries to make Health decisions on it, this is tends to be least effective way to figure out what is healthy for one's own body.

It's not that you're right or wrong, it's that it's a logical game that shouldn't be played to begin with.

There's no reason to believe that logically working through biological mechanisms to then decide what is healthiest for the organism will work.

It can be a guide in some way but the way you're using it is so specific and there's so many mechanisms involved that in practicality drinking the blood can still be the right decision.

In the overall picture here drinking the blood can be better than the iron supplements, considering all the pros and cons and everything involved. But when people are stuck in the epistemology of epidemiology mechanistic logic then they could easily find themselves making suboptimal Health decisions on ghost fears.

Edited 3 hours ago by integral

[PsychedelicEagle]

1 hour ago, integral said:

In the overall picture here drinking the blood can be better than the iron supplements, considering all the pros and cons and everything involved. But when people are stuck in the epistemology of epidemiology mechanistic logic then they could easily find themselves making suboptimal Health decisions on ghost fears.

In the overall picture here drinking the blood can be worse than the iron supplements, considering all the pros and cons and everything involved. But when people are stuck in denying the epistemology of epidemiology mechanistic logic then they could easily find themselves making suboptimal Health decisions on ghost fears.

[integral]

2 minutes ago, PsychedelicEagle said:

In the overall picture here drinking the blood can be worse than the iron supplements, considering all the pros and cons and everything involved. But when people are stuck in denying the epistemology of epidemiology mechanistic logic then they could easily find themselves making suboptimal Health decisions on ghost fears.

You're a playful guy. It's too bad we couldn't understand each other.

[aurum]

This really undermines his whole project.

No way you're achieving biological immortality if you can't even beat AIG.

[Leo Gura]

One of the clearest problems with rationalism is the use of narrow metrics in healthcare as a proxy for good health, as if health can be reduced down to a few numbers on a page. Health is a much more subtle topic than that. You never really know how healthy someone is.

Edited 1 hour ago by Leo Gura

[Leo Gura]

5 hours ago, OBEler said:

He looks sick. He will put all his energy to fight this disease. Maybe you can contact him and help him out what worked for you? 

The only advice I have for him is LDN and carnivore diet. I'm sure he can figure that out himself. Peptides might be useful too. I have yet to try that.

It will be interesting to see what his research reveals over time. He's got nothing better to do than chase this issue down. I am sick of chasing this issue because hardly anything works.

Edited 1 hour ago by Leo Gura