Trying Out a 4-Substituted Tryptamine & More

[Leo Gura]

THCA isolate is also extremely cheap. You can buy a lifetime supply for $100.

It is the ideal chemical. People who buy/smoke weed are conformist idiots.

Edited November 19 by Leo Gura

[LambdaDelta]

7 minutes ago, Leo Gura said:

THCA isolate is also extremely cheap. You can buy a lifetime supply for $100.

It is the ideal chemical. People who smoke weed are conformist idiots.

That's also what I'm finding out. Quite amazing how simple decarboxylation bypasses the regulation. Just what kind of morons write these laws? It's stranger than with RCs because of the massive consumption scale. Seems even cheaper than synthetics like JWH. Weed is aboriginal muck with an obscene smell, truly we're still in the dark ages. 
I'll get a gram even though I'm not good friends with cannabinoids, at worst it can just be shared with others. 

[Funkypants]

@Leo Gura

15 minutes ago, Leo Gura said:

THCA isolate is also extremely cheap. You can buy a lifetime supply for $100.

It is the ideal chemical. People who buy/smoke weed are conformist idiots.

What is it about using THCA isolate that makes it one your top chemicals?

[Leo Gura]

16 minutes ago, Funkypants said:

@Leo Gura

What is it about using THCA isolate that makes it one your top chemicals?

For me it is more potent than 5-MeOs.

THC makes 5-MeO look easy.

The only thing than can compete with THC is Salvinorin.

Edited November 19 by Leo Gura

[Nemra]

4 minutes ago, Leo Gura said:

For me it is more potent than 5-MeOs.

Doesn't that depend on the dosage of 5-MeO-DMT?

[Leo Gura]

5 minutes ago, Nemra said:

Doesn't that depend on the dosage of 5-MeO-DMT?

Sure, but there other also other qualitative factors which cannot be quantified. And it lasts 5x longer.

One of the problems with 5-MeO is that it is too short.

Edited November 19 by Leo Gura

[Funkypants]

5 minutes ago, Leo Gura said:

For me it is more potent than 5-MeOs.

THC makes 5-MeO look easy.

The only thing than can compete with THC is Salvinorin.

@Leo Gura  Would you recommend this chemical to a complete newbie? 

[Nemra]

@Leo Gura, what about N,N-DPT?

Why is that chemical not an S-tier for you?

 

[Leo Gura]

36 minutes ago, Funkypants said:

@Leo Gura  Would you recommend this chemical to a complete newbie? 

For most people it won't be psychedelic.

I have a very unusual relationship to cannabinoids.

33 minutes ago, Nemra said:

@Leo Gura, what about N,N-DPT?

Why is that chemical not an S-tier for you?

It changed how it affects me. It used to be better, then it got worse. It's not as clear for me as the others.

DPT can be S-tier for people. Just not for me. It's a very strange chemical with huge potential. I wish it worked on me like it used to. Not sure why it changed for the worse.

Edited November 19 by Leo Gura

[Nemra]

11 minutes ago, Leo Gura said:

It changed how it affects me. It used to be better, then it got worse. It's not as clear for me as the others.

Does it leave you in confusion?

Does it worsen your health?

18 minutes ago, Leo Gura said:

DPT can be S-tier for people. Just not for me. It's a very strange chemical with huge potential. I wish it worked on me like it used to. Not sure why it changed for the worse.

It is strange indeed.

I hope it doesn't get worse for me.

It lasts extremely long.

[Leo Gura]

1 hour ago, Nemra said:

Does it leave you in confusion?

It takes me to insanity consciousness.

Not bad per se, but difficult to make something useful out of it.

1 hour ago, Nemra said:

Does it worsen your health?

I'm not sure.

[Nemra]

@Leo Gura, could it be possible that psychedelics may have heightened your sensitivity and changed what you experience on some of them?

1 hour ago, Leo Gura said:

It takes me to insanity consciousness.

Is everything dysfunctional in that state?

Also, have 4-AcOs and 4-HOs gotten worse or have they always been weak for you?

I cannot imagine 4-HO-MET not being amazing.

Edited November 19 by Nemra

[Leo Gura]

2 hours ago, Nemra said:

@Leo Gura, could it be possible that psychedelics may have heightened your sensitivity and changed what you experience on some of them?

Yes. That's likely what happened.

Quote

Is everything dysfunctional in that state?

Not really, it's just very hard to relate to human life. Like a twisted dream.

Quote

Also, have 4-AcOs and 4-HOs gotten worse or have they always been weak for you?

They got better I would say.

Mushrooms became more 5-MeO-like.

Quote

I cannot imagine 4-HO-MET not being amazing.

I'm not a big fan of 4-HOs. They just tend to not be as good as the 5-MeO's. Why do them when 5-MeO exists?

I don't like the 4-HOs and 4-AcO's due to them having tolerance and I don't want to be limited by that.

But they can also be great, don't get me wrong. These are just my perferences.

Edited November 19 by Leo Gura

[ZenSwift]

On 24/10/2025 at 6:24 AM, Leo Gura said:

 

@Leo Gura

 

What allowed Leo to be so ballsy with practices of Ego dissolution? 

I've noticed that as I deepen into the work, a high DESIRE for truth needs to be at the spearhead. A desire do strong that you're willing to sack up and do a breakthrough dose of 5meodmt. 

How did you strengthen your relationship to truth so much? To motivate you to break through to the terrifying levels of Awakening? 

How did you increase your capacity for truth? 

I feel like there has to be a mega willingness to suffer through it all. 

 

How has your relationship to fear evolved in pursuing this work? 

 

I've noticed fear is holding me back. 

[Nemra]

59 minutes ago, Leo Gura said:

I'm not a big fan of 4-HOs. They just tend to not be as good as the 5-MeO's. Why do them when 5-MeO exists?

I don't like the 4-HOs and 4-AcO's due to them having tolerance and I don't want to be limited by that.

10 mg of 4-HO-MET was superb, but I don't know if it was significantly boosted by the previous trip. It would be nice if it didn't build tolerance. I liked the feeling it gave me. It wouldn't let me get distracted by fear.

I wanted to go for a higher dose of 5-MeO-DMT, but I couldn't. One thing I didn't like was that my head felt more heavy and locked. However, I didn't expect so much clarity of experience.

59 minutes ago, Leo Gura said:

But they can also be great, don't get me wrong. These are just my preferences.

Ok.

Edited November 19 by Nemra

[Leo Gura]

56 minutes ago, ZenSwift said:

@Leo Gura

 

What allowed Leo to be so ballsy with practices of Ego dissolution? 

I've noticed that as I deepen into the work, a high DESIRE for truth needs to be at the spearhead. A desire do strong that you're willing to sack up and do a breakthrough dose of 5meodmt. 

How did you strengthen your relationship to truth so much? To motivate you to break through to the terrifying levels of Awakening? 

How did you increase your capacity for truth? 

I feel like there has to be a mega willingness to suffer through it all. 

How has your relationship to fear evolved in pursuing this work? 

You're not quite looking at it the right way.

I LOVE Reality. That is the only motivation.

Nothing else matters. It's done for love of Reality.

When you love Reality, the costs are irrelevant. You would do anything for your child. And I will do anything to understand Reality.

You are forgetting to love reality.

Edited November 19 by Leo Gura

[Xonas Pitfall]

@Leo Gura I’m not sure if you've mentioned or revealed this yet, but what was the compound you used when you reached Alien Awakening? I’d be curious to know!

[Xonas Pitfall]

On 11/17/2025 at 8:39 PM, Leo Gura said:

• DMT
• 5-MeO-DMT
• 5-MeO-MALT
• THC
• Salvinorin A

Also, in case anyone knows, which of these would you say has the most 'sedating/numbing of movements' effect? One problem I tend to notice on most of my trips is unwanted movement and actions, which is why I've been more hesitant to try out Salvia and Salvia-alikes, at least not yet. 

[Leo Gura]

1 hour ago, Xonas Pitfall said:

@Leo Gura I’m not sure if you've mentioned or revealed this yet, but what was the compound you used when you reached Alien Awakening? I’d be curious to know!

I've done it on various chems, but the deepest one I don't share because it was a lethal combination.

It is less about the chem and more about the depth of your comprehension of consciousness.

5-MeO is enough. Salvia is also a good candidate for that.

Edited November 19 by Leo Gura

[Xonas Pitfall]

10 minutes ago, Leo Gura said:

I've done it on various chems, but the deepest one I don't share because it was a lethal combination.

It is less about the chem and more about the depth of your comprehension of consciousness.

5-MeO is enough. Salvia is also a good candidate for that.

@Leo Gura What would you say is a good lifetime supply for 5-MeO?