Is it posible to reach 5-MeO states by meditating?

[Psychonaut]

I have been meditating for years and have also had some Samadhi like experiences after 4-5 hrs of meditation.

But no way you will reach anywhere close to a high dose 5-Meo-DMT trip. My last two trips were both 80mg and they have completely rewired my brain. 

[Oppositionless]

I actually think meditation and self enquiry can be really powerful when paired with a hardcore philosophical inquiry into God. The problem is no one does that .