forestfog

With the direct Emesh vaporizer you burn the remaining residues as a routine, although normally after optimal vaping of pure 5-MeO freebase there hardly are any residues on the mesh. I can't think of anything more convenient. Demonstrated on the video at 4:36.

After using the manual Eclipse vape for years, few months ago I got into the Emesh vaping technique and imo it's definitely worth the investment. Very cost effective, I would estimate one needs a third of the normal dose and even the experience feels smoother, similar to snorting/plugging. But if you use the oil pipe, a normal lighter works well for freebase 5-MeO, no need for a torch.

Meanwhile Mindset Pharma is hopeful that their molecule will be therapeutically (maybe metaphysically also?) better than 5-MeO-DMT. "Mindset Pharma Announces Further Preclinical Results Demonstrating Strong Efficacy and Improved Safety Profile for its 5-MeO-DMT-Inspired Drug Candidate, MSP-4018 TORONTO, Sept. 20, 2021 (GLOBE NEWSWIRE) -- Mindset Pharma Inc. (CSE: MSET) (FSE: 9DF) (OTCQB: MSSTF) ("Mindset" or the "Company"), a drug discovery and development company focused on creating optimized and patentable next-generation psychedelic medicines to treat neurological and psychiatric disorders with unmet medical needs, today announced that preclinical proof-of-concept data comparing its clinical candidate, MSP-4018, against 5-MeO-DMT further demonstrated strong efficacy and an improved safety profile as a next generation psychedelic medicine. “Given the strong preclinical efficacy and safety data in support of MSP-4018, combined with our expedited manufacturing process, we believe our Family 4 clinical candidate has the potential to provide a safer and more scalable therapeutic alternative to first-generation 5-MeO-DMT. We believe this preclinical data will enable us to quickly advance this novel compound into human clinical trials,” said James Lanthier, CEO of Mindset. “The latest preclinical proof-of-concept data showed that, in addition to its strong efficacy, both locomotor activity and rearing behavior for MSP-4018 did not decline at a range of doses tested, compared to the profound decline observed in 5-MeO-DMT, indicating a remarkably improved safety profile for MSP-4018. In addition, we saw further evidence of psychedelic activity, reflected in the head twitch response of mice,” concluded Joseph Araujo, Chief Scientific Officer of Mindset. Mindset’s Family 4 compounds are DMT and 5-MeO-DMT-inspired novel drug candidates that offer a broad range of pharmacological diversity suitable for in-clinic settings. The Company has run a battery of specialized in-vitro and in-vivo tests on its patent-pending novel compounds to select the optimal psychedelic drug candidates for progressing towards human clinical trials. To watch a video of Mindset’s CEO discussing the announcement in greater detail, please visit: https://youtu.be/JeyBUp2klXk."

Recently Bernardo Kastrup wrote about the lack of understanding by Sam Harris of consciousness as fundamental (ontological idealism). "Indeed, idealism is one of the foundational topics in both Eastern and Western philosophy. A basic understanding of idealist claims—the claims of Berkeley, Swedenborg, Kant, Hegel, Schopenhauer, and arguably even Plato, Parmenides and Empedocles—is part of the 'ABC' of philosophy. That someone who "received a degree in philosophy from Stanford University and a Ph.D. in neuroscience from UCLA" (quote from Harris's website) can fail so resoundingly at such a foundational level is, well, quite amazing. Harris conflates very basic concepts. For instance, he conflates personal consciousness with consciousness as ontic category, something no self-respecting philosophy freshman would do (it's like conflating a wooden table with wood). Parts of his 'argument against idealism' also imply a direct conflation of idealism with solipsism, two entirely different metaphysics that, again, no self-respecting freshman in philosophy would conflate. How is that possible?" https://www.bernardokastrup.com/2021/06/is-ad-hominem-always-fallacy.html

I agree with your point in general, but I wonder makes you describe Martin as "just some hippie dude" doing "shamanic work"? Is this some rhetorical expression or you genuinely think these are accurate definitions? Martin has deconstructed the shamanic paradigm in the psychedelic scene and many people dislike him because of this. Also hard to see Martin as a hippie. In your interview with him, you seemed to respect his experience and views about 5-MeO. That video seems to be one of the most watched videos on YT. For now the testimonials that have come out from Martins clients have praised his work and how he was very attentive in the session between hits if they didn't want to go further with the experience. He certainly did things that might seem weird, but he explains that taking 5-MeO along with the client was for him enter the same energetic space with the client to perceive more accurately the energetic blockages etc. Do you find this inconceivable?

@High-valance clear explanation. As I perceive it, Martin Ball, @Leo Gura, Rupert Spira and Bernardo Kastrup are all contemporaries that basically agree on the fundamentals, but communicate it a bit differently.

For contextualisation, it seems that the OPs comment is a response to some Rupert Spiras youtube talk. It seems that Rupert Spiras nonduality version and its "direct path" method has lot in common with ideas advocated on this forum about the nature of consciousness.

@machii From your OP description there is a good probability that I have been getting my 5-MeO from the same source. Before their current HCL and freebase options, they used to have it in oxalate salt form. Personally never tested it, but from their different batches (slight colour differences) and salt forms I have always got a solid 5-MeO experience, and the toad venom that I got some years ago before the synth was available feels nowadays pretty obsolete...even a bit disgusting to be honest. Go slowly and do not underestimated the power of it when administrated optimally.

@Gneh Onebar Very true on how to describe the experiences they necessarily will have a dualistic sense. I have listened to Baches interviews and just recently bought the book which I'm looking forward to read even more after your opinion of it. It certainly seems to be a landmark in psychonautics. Not that the book would give me the answers, but personally I'm especially interested if such high doses of LSD experiences have the same inner consistency cross individuals that 5-MeO seems to deliver. Then I'm curious to read more on why Bache thinks that he could have "gone slower" on his explorations and on his difficulties in integrating his experiences to his ordinary life.

In this James Jesso's interview Bache responds to the question about 5-MeO-DMT starting at 32:15. From it I personally get the sense that Bache is not very familiar with 5-MeO-DMT specially with the more long lasting effects of other ROAs than vaping. Even though his perspective on how there is infinite layers of ultimacy and one should be cautious on drawing conclusions from single experiences is a valid one, I can't avoid to speculate that his observations have still an dualistic element to them that possibly would not exist if he would have explored consciousness with 5-MeO-DMT. But this is merely based on his descriptions as I personally have not done such high doses of LSD.