The cockroach gene.

[integral]

Quote

 

Here is the comprehensive list of the APO (Apolipoprotein) gene family variants, categorized by how they determine your "resilience" to toxins, diet, and lifestyle stressors.

1. APOA-1 Milano (The "Superhero" Variant)

What it is: A rare mutation of the APOA-1 gene first found in Limone sul Garda, Italy.

In Layman’s Terms: This is the ultimate "get out of jail free" card. It produces a hyper-active version of "good" cholesterol that acts like a biological power-washer. It clears toxins and fat out of the arteries so quickly that carriers can often eat poorly and smoke while maintaining the heart health of an athlete.

2. APOE2 (The "Golden Ticket" Longevity Gene)

What it is: One of the three common versions of the APOE gene.

In Layman’s Terms: The "Bulletproof" gene. It is highly efficient at repairing cells and clearing out the "junk" that causes aging. It is found in a massive percentage of people who live to 100, even those who didn't live a "perfect" lifestyle.

3. APOE3 (The "Standard" Baseline)

What it is: The most common version of the gene (found in ~75% of people).

In Layman’s Terms: The "Fair" gene. You don't have a special shield, but you aren't at high risk either. Your health and longevity will mostly be a direct result of your choices—if you smoke and drink, your body will show the damage at a normal rate.

4. APOE4 (The "Fragile" Variant)

What it is: The version of the gene associated with high cholesterol and Alzheimer's risk.

In Layman’s Terms: The "Glass House" gene. This version is very bad at clearing toxins. People with this gene are much more sensitive to environmental stressors like cigarette smoke or heavy alcohol, which cause damage to their brain and heart much faster than in other people.

5. APOB (The "Toxin Carrier" Marker)

What it is: Not just a variant, but a gene that produces the "packaging" for bad cholesterol.

In Layman’s Terms: The "Garbage Truck." If you have a genetic mutation that keeps your ApoB levels very low, it means you have fewer "trucks" available to carry toxins into your artery walls. People with naturally low ApoB are often the ones who can "do whatever they want" and never develop heart disease.

6. APOC3 (The "Triglyceride Shield")

What it is: A gene that regulates how fat is cleared from the blood.

In Layman’s Terms: The "Fast Burner." Certain rare mutations in this gene make it so that no matter how much fat or sugar a person eats, their blood stays clear of triglycerides. This provides a massive layer of resilience against the metabolic damage of a "modern" diet.

 

APOE2 is the smoke and drink your entire life and live to 100 gene. 

The rock has it. He got tested.