Is it simply genetics?
I’m talking about people like Donald Trump, John Mcafee, the Rock, etc. in the celebrity realm. And even my Uncle
My Uncle smokes 20 cigarettes a day, drinks probably 250 ml whiskey daily, and he has been doing it for 40 years. He sleeps only for like 5 hours. He’s now 60, and he has remarkable energy levels. He’s active for like 16-18 hours a day, no joke. Also I’ve literally never seen him fall sick. Not even once. All he eats is junk food
Mcafee has said during his days building the antivirus software, he would go days without sleep. He did so even during his 70s, RIP
Trump, who is almost 80 years old, apparently never exercises, sleeps only 3-4 hours a day on average, never drinks water, 12 diet cokes a day, highly processed food diet. All of this has been confirmed by Dana White, and many others. Sometimes he doesn’t sleep for 2-3 days even. Even his medical records are immaculate. Though he has said he’s never smoked or had alcohol.
Despite all this, he seems to have an amazing level of energy, to get everything done.
Is it possible to achieve this power?

Happiness in your "human form" is 100% conditional. To understand this, it’s best to observe yourself as an organism. An organism cannot grow, live, or sustain itself without the right conditions. Some animals need cold winters, others are more social and depend on having a group or tribe, and some require very specific reproductive strategies, etc. We are the same. And because we are one of the more complex organisms, our needs are far more niche, precise, and heavily conditional. Just turn off your heating or electricity for a day, and you’ll quickly see how conditional your happiness and well-being truly are.
The more "meditative" or "enlightened" type of happiness is often described as unconditional. In this state, you’re in such a high state of awareness that whatever conditions you’re in, you recontextualize them as part of understanding yourself as an observer of reality, or as one with oneness, God, or existence itself. You’re so completely detached from your human self that it wouldn’t matter if you cut off your arm right then and there. You’d just perceive it as part of "exploration, understanding, and Love." That’s often what drug addicts, especially heroin users, experience. If you ask them why they keep running their lives the way they do and continue taking heroin, they’ll often say, "Well, it’s because heroin takes it all away and makes it feel good." These states are beautiful but highly dysfunctional and dangerous to your human self.
However, this state is incredibly difficult to maintain, especially if you still want your human self to function and participate in "human society." It’s so impractical that it’s almost useless to think about unless you’re planning to fully commit to the path of a monk or yogi who meditates 24/7 and is supported by others in a monastery.
If you don’t plan to go down that path, then yes: happiness is 100% conditional. You need to accept that and carefully define the conditions, preferences, and actions you want to build your life around in order to feel good.