What Am I

The PH strip is to determine comfort in vaping by targeting a PH at a neutral level relevant to the human body. It's only related to safety in so far as it's probably not great to inhale something that's too acidic or too basic. The idea behind the potential safety of the method has more to do with the lower temperature the e-liquid devices use. The example given in the first link mentions the fumarate decomposition temperature of 300C as opposed to the vape device operating temperature of 200C. In theory, the old worry of fumaric acid decomposing into a toxic chemical when vaped wouldn't apply here. You make a good point though that it's difficult for people like you and I to actually know whether or not it's safe. It's not like we have a lab setup performing the necessary testing. In the absence of better data, it's up the individual to decide the level of risk they want to take based on the available information. Though I'd somewhat counter that the original fear of vaping salts in e-liquid might have been formed based on similar amounts of hearsay and lack of data.

I don't have direct experience with 4-AcO-DMT, but I see no reason it couldn't be mixed with e-juice and vaped. I believe I've seen posts on the /r/researchchemical subreddit where people were doing just that. As you can imagine, it'd likely hit much quicker with more intensity. It's also possible the general experience would be different from eating it since I don't believe vaping would convert it to 4-HO-DMT. As far as vaping fumarate and other salts in e-juice, I made a post about this a little while ago. The common opinion maintains that it shouldn't be done, but experimentation has been occurring over at DMT-Nexus that begs to differ. I've been following the threads since they began, and I can attest to psychedelic salt vaping being perfectly fine and even superior. Again though, this is only in the context of e-juice. I've heard vaping salts straight up is quite unpleasant. Edit: Since making this post, I've learned 4-subbed tryptamines react especially poorly in solution. The color quickly changes to a dark brown/black. It's not clear if it affects potency, but it certainly doesn't seem like a positive indicator.

Agreed, it could be the very thing that helps someone cross that seemingly insurmountable gap of authentic awakening. Admittedly, I'm making my judgement of a retreat's effectiveness for myself without ever having attended one. It's something to keep an open mind about I guess. To my knowledge, I've never been in the physical presence of someone who's seriously skilled and awakened. I'd love to try that sometime, as it can supposedly produce profound effects on its own via the entrainment caused by their elevated energetic field.

I agree, it's super interesting. The only retreat I'm aware of that utilizes iboga is the retreat ran by Daniel Schmidt from the video, and I believe they're held in Canada. It also looks like there's none happening until later this year: https://awakentheworld.com/blog/samadhi-center-meditation-retreats/ I'm personally much more interested in taking the concept of utilizing iboga TA extract microdoses for meditation and applying it in the privacy of my own home. Some people do better in a ceremony or retreat environment, which I totally understand and respect, but I think I've always done better on my own. Though I could certainly see the benefit if you have an exceptionally skilled (ie actually awakened) person running it.

Here's a video that discusses iboga and 5-MeO-DMT use at a meditation retreat. It's an interview with the guy who created the Samadhi series on YouTube, which is an amazing series of videos and worth checking out. Iboga is brought up around the 22:32 mark. The whole interview is pretty cool though.

Here's a few really interesting videos. The first two are Hamilton Morris going into the scientific aspect and describing what makes it so unique among psychedelics. The last is in link form because apparently it's old enough to where YouTube won't allow a video embed. It's Aubrey Marcus describing a high dose TA iboga extract experience. https://www.youtube.com/watch?v=RR9P7ksKktM

I finally got around to watching these. I don't understand why they're so obsessed with tramadol in Africa. I guess it's a question of options, and that might be the only one they have when it comes to opiates/opioids. That first video even had a clip of an African song dedicated to tramadol lol. I guess they're lucky Africa happens to be the home of a natural psychedelic that can help strip them of their addictions. It's my understanding that iboga's many alkaloids are complex tryptamines like no other. They supposedly affect way more receptors than other tryptamines, and even go so far as to affect the receptors involved with salvia. The metabolites stay active in your system for a month. It's super interesting if nothing else. I can't yet speak to whether the subjective effects are desirable.

E-juice psychedelic vaping is certainly the king of redosing in my experience. I've spent hours periodically puffing on the vape getting to different levels of consciousness. It's amazing for exploring various doses and inching forward into ever higher states. Like I mentioned though, it might take a toll on your lungs. The absolute most comfortable redose ROA would probably be subcutaneous injection, but that's understandably a step too far for most people.

Very true. No matter what I say here about how nice it is as an ROA, there's risks that can't be fully mitigated. Also worth mentioning is the use of a micron filter to pass your psychedelic solution through as it enters the airtight sterile vial. This is mentioned in the instructions I posted. It should at least help with purification in terms of bacteria and anything else large enough to be caught in the filter. https://en.wikipedia.org/wiki/Microfiltration

That's funny, peptides are what got me started with injections as well. I had the same phobia of needles as anyone else, but that quickly goes away after the frequent SubQ injections needed for peptide use. After that, the move to psychedelic injection was the obvious next step.

Infection and abscess at the injection site would be the two big risks, but as you've noticed after hundreds of injections (same amount for me), it's safe if done responsibly. Proper technique, cleanliness, and sterility are the keys to safety with injecting.

There's also this cool video presentation to go along with the study:

Here's the guide that originally got me started creating sterile vials of psychedelics. It was posted by the site admin of the 5 Hive forum. This is not an encouragement for anyone here to actually pursue the ROA, but if you truly feel called to it, this is basically how it's done. Just posting for the sake of shared knowledge. It's up to you to apply wisdom in your choices. NOTE: Obviously the ROA mentioned here is intramuscular injection, but you can substitute it for subcutaneous injection. Either one works. So You Want To Intramuscularly Administer 5-MeO-DMT HCl (or other salt) by HumbleVoyager Disclaimer: This information does not condone the activity it describes. Anything attempted is at one's own risk and knowledge that there are serious consequences if anything goes wrong in this process. Risks include, but are not limited to, infection, abscess, psychosis and injuries. This information is provided to help prevent problems that might arise if someone attempted this without appropriate information. Please PROCEED AT YOUR OWN RISK. Materials Required: -1 vial of bacteriostatic water containing .9% benzyl alcohol - 30ml is a good standard size. -Sterile 10ml syringes with luer lock attachment. -Any number of single-use, brand-new insulin syringes. I suggest using 1cc (1 ml) 27 to 31 gauge (31 gauge is nice and EasyComfort brand is ideal), 1/2 inch needles. 1 inch needles if you have a lot of fat in your thigh. -Empty sterile vial with rubber membrane on top (10ml) -.22μm (.22 micrometer) Micron filters. -25 gauge, 1.5 inch hypodermic needles (Note that this is just needles, not with a syringe. These attach to the 10ml syringe.) -Cotton balls or alcohol wipes -Rubbing alcohol (isopropyl alcohol) -Milligram scale (capable of weighing to .001g) -Parchment paper 1. Acquire 5-MeO-DMT in a salted form (5-MeO-DMT HCl, 5-MeO-DMT Fumarate, 5-MeO-DMT Oxalate, etc.). 2. Make a calculation as to how you'd like to dose. I'd say that 10mg/ml is a good concentration. That way if you wanted to dose 5mg, you'd draw up .5cc's in your syringe. When you do an intramuscular injection, you really want as little fluid in there as possible. 3. Boil some water and pour the water into a bowl that has your bacteriostatic water vial in it. Allow the bacteriostatic water jar get hot. A hotter solvent dissolves the compound more quickly and efficiently. 4. While your bacteriostatic water is heating up, weigh out your 5-MeO-DMT. For a 10ml vial, you will need exactly 100mg of 5-MeO-DMT. It is best to weigh this on a square of parchment paper so that you can use the paper to move the powder. 5. Get one of your 10ml syringes, affix a needle onto the end, and remove the plunger. Into the barrel of the syringe, place the total amount of 5-MeO-DMT HCl (in this case you would be putting 100mg 5-MeO-DMT HCl). Then put the plunger back into the syringe, but don't push it down yet. Keep it at the top of the barrel. 6. Get your vial of warm bacteriostatic water. Insert the needle into the vial and turn the vial upside down so the needle is pointing up and push the plunger all the way up to the 5-MeO-DMT powder so that the vial gets filled with air. This will keep a vacuum from forming when removing the bacteriostatic water. Be careful to not go so far as to push any of the 5-MeO-DMT into the vial (this shouldn't be a problem, since you are moving directly to step 5). 5. Begin pulling the syringe back (it should actually be moving back on its own accord because you have created positive pressure in the bac water vial) and draw up 10ml or 10cc's of saline solution into the syringe. Make sure it fills up completely. Once you have 10ml of water in your syringe, remove the needle from the vial but draw up an extra 1cc of air into your vial. 6. Shake/rotate that syringe until the 5-MeO-DMT HCl has completely dissolved. It should just look like clear water when it is completely dissolved. 7. Hold the syringe with the needle facing up. Cap and remove the needle. Set it aside. 8. Screw on the micron filter and then screw on the needle to the output port of the filter. 9. Insert an extra needle into the side of the rubber top of the sterile vial without a syringe. This is to let air come out when you are adding the 5-MeO-DMT solution. 10. Insert the needle that is attached to the micron filter and syringe into your sterile, empty vial and depress the plunger. This will be a bit difficult to do and will require some strength. Be patient and let it go at its own pace. 11. Now your vial is a sterile, filtered solution ready for injections. Label the vial with the substance it contains AND THE CONCENTRATION. For example, this vial would read: 5-MeO-DMT HCl - 10mg/ml 12. Note: ALWAYS use a NEW NEEDLE. NEVER REUSE NEEDLES. You don't want to contaminate the sterile environment in that vial. 13. Now it's time to dose yourself. First, set up a clean, safe environment. Sterilize any surfaces you will be keeping your vial, syringes, and alcohol wipes. I have used a brand new cookie sheet for this purpose and have rubbed the whole thing down with rubbing alcohol to kill any bacteria. Set up any playlist you'd like for the experience at this point. 14. Wash your hands THOROUGHLY. You don't want any bacteria getting anywhere near the inside of your muscle. 15. This is best done with shorts of some kind or naked, because you will need access to your thigh. You can also inject into your deltoid muscle but that can be more painful and is hard to do on yourself. I will just talk about injecting into the thigh. 16. Take a good look at your thigh. You will want to divide it into four equal quadrants. Your injection should happen in the bottom-right quadrant for your right thigh or the bottom-left quadrant for your left thigh. If necessary, draw the quadrant lines. 17. Once you have determined where your injection site will be, sterilize the thigh by rubbing it in an outward spiral motion with your alcohol wipe, from the injection site outward. Take your time and make sure you don't miss a spot. 18. Let the rubbing alcohol dry. 19. Draw up your dose from your vial. Remember to double-check your dose as you do this to make sure you have the correct amount. 20. Hold the syringe in one hand like a dart. With your free hand, spread the skin on your thigh apart so it's tight. This will eliminate or at least significantly minimize any pain when you insert the needle. 21. Insert the needle at a 90 degree angle to your skin. You want to do this in one continuous motion, it doesn't have to be fast. Once it's in, I would suggest not letting the syringe move around so much. You can let go of the skin that is stretched now that the needle is in place and use it to steady the syringe. 22. Pull back on the plunger slightly to make sure you haven't hit any veins or arteries. 23. If there is NO blood registering in the barrel, you are good to go. Inject slowly and steadily. If you feel any pain or severe stinging, slow down your rate of injection. Breathe deeply as you do this. Sometimes people hold their breath. 24. Once you are done injecting, cap your needle and put it on your tray or somewhere that it won't be stepped on or otherwise messed with. 25. Lay down and dream with Love.

The instructions in this video from 1:56 onward are basically identical to my process. The amount of liquid you'd draw into the syringe for your desired dose is dependent on the concentration of your vial. I use a concentration of 100mg per mL of water for 5-MeO-DMT, so 10mg would be 10 units on the syringe.

No doubt, it can definitely be dangerous.

When it comes to SubQ vs IM for the four substances I mentioned above, practically all factors of the ROAs are identical except for the location of injection (fat vs muscle). Meaning the dose, length of trip, time until the trip begins, subjective experience, etc are all the same. It's also painless when you inject into belly fat using a tiny 31 gauge needle like those used for insulin. When an option like this is available, I see no reason to puncture your muscles, which can damage them and create scar tissue over time. For 5-MeO-DMT specifically, 5mg would be a solid trip, 10mg would be bordering on a breakthrough, and 15mg would almost certainly be a full breakthrough. From the time of injection, you have ~5 minutes until it begins, and it'll be peaking at ~10 minutes. Total trip time is about an hour. I've never boofed 5-MeO-DMT, but from the descriptions I've read it's very similar experientially to SubQ/IM. Meaning you're correct in thinking it's a much smoother and longer ride than a rapid ROA like vaping. Let me know if you're curious about anything else. I'm happy to share. I recognize there's a strong (and possibly well deserved) stigma around injection of any recreational substance. I myself once had a similar mindset, and I only began injecting SubQ after a series of interesting coincidences led me there. As I laid out above though, the reality of the situation doesn't seem to match the dogma. That's not to say you can't mess yourself up in a number of ways, and I find it hard to recommend this to anyone who's not incredibly serious about spirituality, and by extension serious about proper psychedelic use. Maturity in your actions and decisions is paramount. Efforts towards sterility should be taken wherever possible. A relatively pure source material, the use of micron filters, and overall good hygiene during injection are all prerequisites. I think I've seen Leo mention that plugging 5-MeO-DMT is the best ROA, and I'd generally agree. Injection literally only has a few tiny advantages, and the risks may not be worth it for 99% of people.

This is pretty accurate in my experience. 5meo is a profoundly powerful tool for activating your body's spiritual energetic system. By doing so, it clears away a lot of the mental baggage that's accumulated over this life, as well as previous lives in all likelihood. The breakthrough experience is comparable to a kundalini activation and nirvikalpa samadhi. Its ability as a substance to accelerate spiritual growth perhaps has no equal. DMT for me is like a tour through the "ten thousand things" mentioned in eastern religions, which is to say it's a demo of the infinite complexity and variability available for experiencing. It can range from heavenly and benevolent, hellish and malevolent, and everything between and beyond. If 5meo is more on the superconscious/god level, DMT is more on the subconscious/soul level. When a trip goes well (which is more often than not thankfully), it's like a hypercharged therapy session mixed with ecstatic happiness and catharsis. DMT is mentally healing, but it hasn't been transformational for me the way 5meo has. In my experience, oral DMT with harmalas is definitely the way to go as opposed to vaping. The experience is slowed way down and stretched way out, which really allows it to reveal its full character. I'd strongly recommend a legit oral dose before giving up on DMT completely.

Thanks so much for sharing. That's interesting to hear that the trip experience differs so much from mushrooms and DMT in the way it's less "out there" and more "right here". That really aligns with what I've been hearing, and it certainly makes sense why it'd be utilized at a meditation retreat. DMT shows you some incredible things, but it's as if you're experiencing the essence of an afterlife-type dimension, and it doesn't always translate that well into skills staying conscious in our everyday lives. Iboga sounds more promising in that aspect. I wasn't expecting the effects to be so strong at those doses. For 1.35g of rootbark to be comparable in intensity to ~2g of mushrooms, that would mean a legit flood dose would be a pretty extreme event. Some of the flood dose numbers I've seen are around 15-20 grams. Though maybe it makes sense, as I've heard iboga flood doses referred to as the "final boss" lol. Comparable to a 5-MeO-DMT breakthrough in its own unique way. Many people rave about the beneficial results. I think the microdose amounts of iboga TA extract I have in mind are closer to the equivalent of 100mg of rootbark. When taken daily, the effect is supposed to accumulate and increase over time due to the crazy long half-life of the iboga alkaloids. The effect is probably much more subtle than the microdose amounts you're using, but you'd be exposed to them for potentially weeks or months at a time. I guess it'll take some experimentation to see which is preferable. This post on DMT-Nexus describes it better than I could: https://forum.dmt-nexus.me/threads/iboga-microdosing-guide.340246/

This guy actually handled salvia better than any other video I've seen. Especially considering the quality of his tripsitter lol. Some people absolutely flip out and try to physically run away as if that'll stop the experience. The guy in this video falls out of a window.

Totally agree here. Ketamine seems to actually dim my consciousness and state of presence. There's also something to be said for how addictive it is. I believe that's an indication of the lesser quality states it's producing. Not to mention the organ damage that can occur with frequent use. There's some horror stories on the /r/ketamine subreddit.

Harmine - https://bountybotanicals.com/harmine-hydrochloride/ THH - https://bountybotanicals.com/tetrahydroharmine-hcl/ I can vouch for the seller, at least for the single transaction I've had. The harmalas seem to be high quality as well. A quick side note on the oral DMT dose: I've seen recommendations on this forum to start at ~100mg, but I'd have to respectfully disagree. When it comes to oral DMT, I think there's some variability between individuals in how much is needed for an equivalent effect. I'd compare it to how some people need to boof much more 5-MeO-DMT. In my experience, 30mg DMT with 150mg total harmalas is enough for a strong trip with heavy visuals and a highly transcendent type of mindspace. Going higher than that pushes into extremes, so 100mg for me would be unthinkable and potentially dangerous (at least mentally if not physically). It sounds like OP is already familiar with their individual dose, so this is more so advice for whoever else may stumble across it.

Harmala extracts should be a way cleaner experience than rue tea, in the sense that you can avoid a large number of chemicals that come along in the tea and produce nausea and other unwanted effects. I agree with@bmcnicho that you should use purified individual harmala extracts and create an ideal ratio. Something like 100mg harmine and 50mg tetrahydroharmine would be similar to a caapi harmala extract. I avoid harmaline entirely, as it's too sedating and overpowering. I've had huge success using these amounts, with the result being some extremely heavenly experiences. @Leo Guraare we allowed to link sources for legal items like harmalas?

This is the main ROA I've used many many times, and exactly how I use ketamine, 5-MeO-DMT, 5-MeO-MALT, and DMT. Most people are aware of IM (intramuscular) injections, but not many are aware you can get essentially identical effects using SC (subcutaneous) injections. It's simple, painless, precise, and practically infallible (no misfires). The ROA typically has a high bioavailability, so you also need less of whatever drug you use compared to most other ROAs. Feel free to ask any questions.