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Psygenlab

5-MeO-pyr-T 5-MeO-DMT like Compounds (5-HT1A) psychedelics

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Posted (edited)

 

 

 

inspiring infos from hamilton

 

5-MeO-DMT / 5-MeO-MALT / DPT are known by Actualized.org

 

rarer psychedelics like 5-MeO-pyr-T has crazy affirmity and selectivity-

 

Selectivity: selectivity makes one compound stronger for specific purpose, LSD has strong affirmity for 5-ht1a as 5meodmt,
yet as equal selectivity to 5-ht1a which it makes it also too visual.

 

Screenshot 2025-07-17 215111.png

5-MeO-pyr-T series sound so cool. they could last potentially longer

 

Screenshot 2025-07-17 215105.png

 

Edited by Psygenlab

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Oberlender personally self-experimented with some of the psychoactive drugs synthesized in the Nichols lab.[3] In the mid-1990s, he tried the obscure psychedelic tryptamine 5-MeO-pyr-T, a synthetic analogue of 5-MeO-DMT, and accidentally took too high of a dose of it without a trip sitter present.[3] While under the influence of 5-MeO-pyr-T, Oberlender stripped naked, began wandering the Purdue University campus in a fugue state, and was apprehended by campus police.[3] His case did not end up going to court, but the incident did result in Oberlender having to leave Nichols's lab.[3] His experience with 5-MeO-pyr-T was subsequently published anonymously in Alexander Shulgin's 1997 book TiHKAL (Tryptamines I Have Known and Loved).[3][7] The chemist publicly shared further details of the incident during an interview with psychedelic journalist Hamilton Morris in 2021, describing it as a cautionary tale of the risks of self-experimentation with little-known psychoactive drugs and the importance of careful dose escalation and of having a trip sitter

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DOSAGE : 0.5 - 2 mg, orally DURATION : several hours QUALITATIVE COMMENTS :

 

(with 0.5 mg, orally) "This stuff is an absolute poison. Within minutes I noticed what can only be called ear-ringing without any ear-ringing. Intense tinnitus with no sound, most uncomfortable. There were two waves of nausea and vomiting of yellow bilious stuff, with thick mucus for saliva. I can't think straight -- muddled. I can't get answers to questions because I simply cannot form the questions. Eyes closed to music gave no images, but the music sounded OK. Recovery was quite rapid, and I was together again in a few hours. Never again."

 

(about 1 mg, smoking) "I managed to vaporize about a milligram of the material, and there was nothing profound. There was a slight feeling of calmness. As I felt sure that this material would be a quieting agent, I managed to vaporize and inhale what might have been up to another milligram. There were no psychedelic effects manifested, and I fell asleep easily 10 minutes later."

 

(with 3 mgs, smoking) "Initially the compound exhibited a 5-MeO-DMT-like effect. There was a total loss of self-identity in a nearly instantaneous rush. I felt as if the top of my head was blown off at the inset of the drug experience. My observers told me that I had been unconscious for four hours. I remember reentering with the feeling 'God is Love.' After completely coming to, I felt very nauseous, and threw up in the bathroom several times. I felt drained and sick for the rest of the evening as well as mentally slow. By the next morning I was more alert and responsive, I have absolutely no memory of anything that transpired while I was on the compound."

 

(with 3 mgs, smoking) "I inhaled the vaporized sample at 10 past noon. There was quite a rush. There were none of the shifting shapes, colors and forms of DMT. Nor was it acute with clarity or energy as with my many experiences with 5-MeO-DMT. The effect was intense but not terrifying, with a full body buzz and with humming resonance as I fell backwards into something where all memory was lost. I was told that at 18 past noon, I was unconscious. Something over an hour later, I started flailing, rolling about, quivering and shaking, and had very constricted pupils. In another hour I was able to talk lucidly, but quietly. In yet another hour, I was nauseous and tried for the bathroom, but didn't make it. The people who were watching me were alarmed. My actions were scary. And my skin looked funny for several days afterwards. There are longlasting properties of this. My first exposure was with perhaps a milligrams (smoked, also) and the effects were substantial, with rough edges and minor dysphoria."

 

(with 4 mgs, smoking) "This was the free base. I remember the pipe, and the inhalation and, with the pouring of a small glass of scotch, I settled down in front of the TV to watch a re-run of Star Trek. That was it. I came to some time later in the front room of a professional ally of mine, who had by chance discovered me walking down the street near his house. I do not recall, nor have I been able to regain any memories of the time I was 'out there.' I apparently experienced no physical discomfort from the drug. In fact I distinctly remember feeling very comfortable when I awoke. Clearly this compound is some weird-ass shit."

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